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Selective toxicity of nitracrine to hypoxic mammalian cells.

Hypoxic cells in solid tumours are resistant to ionizing radiation and may be refractory to treatment by many chemotherapeutic agents. For these reasons the identification of drugs with selective toxicity towards hypoxic cells is an important objective in cancer chemotherapy. Nitroimidazoles such as...

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Detalhes bibliográficos
Main Authors: Wilson, W. R., Denny, W. A., Twigden, S. J., Baguley, B. C., Probert, J. C.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1984
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1976693/
https://ncbi.nlm.nih.gov/pubmed/6696822
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