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Synthetic genetic polymers capable of heredity and evolution

Genetic information storage and processing rely on just two polymers, DNA and RNA. Whether their role reflects evolutionary history or fundamental functional constraints is unknown. Using polymerase evolution and design, we show that genetic information can be stored in and recovered from six altern...

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Detalhes bibliográficos
Main Authors: Pinheiro, Vitor B., Taylor, Alexander I., Cozens, Christopher, Abramov, Mikhail, Renders, Marleen, Zhang, Su, Chaput, John C., Wengel, Jesper, Peak-Chew, Sew-Yeu, McLaughlin, Stephen H., Herdewijn, Piet, Holliger, Philipp
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3362463/
https://ncbi.nlm.nih.gov/pubmed/22517858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1217622
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