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Kinase-dependent activation of voltage-gated Ca(2+) channels by ET-1 in pulmonary arterial myocytes during chronic hypoxia
Exposure to chronic hypoxia (CH) causes pulmonary hypertension. The vasoconstrictor endothelin-1 (ET-1) is thought to play a role in the development of hypoxic pulmonary hypertension. In pulmonary arterial smooth muscle cells (PASMCs) from chronically hypoxic rats, ET-1 signaling is altered, with th...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Physiological Society
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3362260/ https://ncbi.nlm.nih.gov/pubmed/22387294 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00396.2011 |
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