Combined inhibition of aromatase activity and dihydrotestosterone supplementation attenuates renal injury in male streptozotocin (STZ)-induced diabetic rats

Our previous studies showed that streptozotocin (STZ)-induced diabetic male rats have increased estradiol and decreased testosterone levels that correlate with renal injury (Xu Q, Wells CC, Garman GH, Asico L, Escano CS, Maric C. Hypertension 51: 1218–1224, 2008). We further showed that either suppl...

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Bibliographic Details
Main Authors: Manigrasso, Michaele B., Sawyer, R. Taylor, Hutchens, Zachary M., Flynn, Elizabeth R., Maric-Bilkan, Christine
Format: Artigo
Language:Inglês
Published: American Physiological Society 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3362176/
https://ncbi.nlm.nih.gov/pubmed/22301628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00569.2011
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