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Inhibition of estradiol synthesis attenuates renal injury in male streptozotocin-induced diabetic rats

We previously showed that the male streptozotocin (STZ)-induced diabetic rat exhibits decreased circulating testosterone and increased estradiol levels. While supplementation with dihydrotestosterone is partially renoprotective, the aim of the present study was to examine whether inhibition of estra...

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Detalhes bibliográficos
Main Authors: Manigrasso, Michaele B., Sawyer, R. Taylor, Marbury, David C., Flynn, Elizabeth R., Maric, Christine
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3174551/
https://ncbi.nlm.nih.gov/pubmed/21653631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00718.2010
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