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C-peptide preserves the renal microvascular architecture in the streptozotocin-induced diabetic rat

AIMS: C-peptide is renoprotective in type 1 diabetes, however, the mechanisms of its actions are not completely understood. We hypothesized that C-peptide attenuates diabetes-associated renal microvascular injury. METHOD: After 4 or 8 weeks of streptozotocin (STZ)-induced diabetes, rats received eit...

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Détails bibliographiques
Auteurs principaux: Flynn, Elizabeth R., Lee, Jonathan, Hutchens, Zachary M., Chade, Alejandro R., Maric-Bilkan, Christine
Format: Artigo
Langue:Inglês
Publié: 2013
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3818424/
https://ncbi.nlm.nih.gov/pubmed/23994433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jdiacomp.2013.07.002
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