Cadmium-mediated toxicity of lung epithelia is enhanced through NF-κB-mediated transcriptional activation of the human zinc transporter ZIP8

Cadmium (Cd), a toxic heavy metal and carcinogen that is abundantly present in cigarette smoke, is a cause of smoking-induced lung disease. SLC39A8 (ZIP8), a zinc transporter, is a major portal for Cd uptake into cells. We have recently identified that ZIP8 expression is under the transcriptional co...

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Détails bibliographiques
Auteurs principaux: Napolitano, Jessica R., Liu, Ming-Jie, Bao, Shengying, Crawford, Melissa, Nana-Sinkam, Patrick, Cormet-Boyaka, Estelle, Knoell, Daren L.
Format: Artigo
Langue:Inglês
Publié: American Physiological Society 2012
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3362162/
https://ncbi.nlm.nih.gov/pubmed/22345571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00351.2011
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