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CXCR4 regulates migration of lung alveolar epithelial cells through activation of Rac1 and matrix metalloproteinase-2

Restoration of the epithelial barrier following acute lung injury is critical for recovery of lung homeostasis. After injury, alveolar type II epithelial (ATII) cells spread and migrate to cover the denuded surface and, eventually, proliferate and differentiate into type I cells. The chemokine CXCL1...

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Bibliografski detalji
Glavni autori: Ghosh, Manik C., Makena, Patrudu S., Gorantla, Vijay, Sinclair, Scott E., Waters, Christopher M.
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3362158/
https://ncbi.nlm.nih.gov/pubmed/22345572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00321.2011
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