Insulin-like growth factor-I stimulates differentiation of ATII cells to ATI-like cells through activation of Wnt5a

Alveolar type II (ATII) epithelial cells play a crucial role in the repair and remodeling of the lung following injury. ATII cells have the capability to proliferate and differentiate into alveolar type I (ATI) cells in vivo and into an ATI-like phenotype in vitro. While previous reports indicate th...

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Main Authors: Ghosh, Manik C., Gorantla, Vijay, Makena, Patrudu S., Luellen, Charlean, Sinclair, Scott E., Schwingshackl, Andreas, Waters, Christopher M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3743013/
https://ncbi.nlm.nih.gov/pubmed/23709620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00014.2013
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