The multifunctional Ca(2+)/calmodulin-dependent kinase II regulates vascular smooth muscle migration through matrix metalloproteinase 9

The multifunctional CaMKII has been implicated in vascular smooth muscle cell (VSMC) migration, but little is known regarding its downstream targets that mediate migration. Here, we examined whether CaMKII regulates migration through modulation of matrix metalloproteinase 9 (MMP9). Using CaMKIIδ(−/−...

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Detalhes bibliográficos
Main Authors: Scott, Jason A., Xie, Litao, Li, Hui, Li, Weiwei, He, Julie B., Sanders, Philip N., Carter, A. Brent, Backs, Johannes, Anderson, Mark E., Grumbach, Isabella M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Vascular Biology and Microcirculation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3362103/
https://ncbi.nlm.nih.gov/pubmed/22427508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00978.2011
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