The Multifunctional Ca(2+)/Calmodulin-Dependent Kinase IIδ (CaMKIIδ) Regulates Arteriogenesis in a Mouse Model of Flow-Mediated Remodeling

OBJECTIVE: Sustained hemodynamic stress mediated by high blood flow promotes arteriogenesis, the outward remodeling of existing arteries. Here, we examined whether Ca(2+)/calmodulin-dependent kinase II (CaMKII) regulates arteriogenesis. METHODS AND RESULTS: Ligation of the left common carotid led to...

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Hauptverfasser: Scott, Jason A., Klutho, Paula J., El Accaoui, Ramzi, Nguyen, Emily, Venema, Ashlee N., Xie, Litao, Jiang, Shuxia, Dibbern, Megan, Scroggins, Sabrina, Prasad, Anand M., Luczak, Elisabeth D., Davis, Melissa K., Li, Weiwei, Guan, Xiaoqun, Backs, Johannes, Schlueter, Annette J., Weiss, Robert M., Miller, Francis J., Anderson, Mark E., Grumbach, Isabella M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3738514/
https://ncbi.nlm.nih.gov/pubmed/23951185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0071550
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