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Oncogenic KRAS regulates BMP4 expression in colon cancer cell lines

Activating mutations in the KRAS oncogene are common in colorectal cancer. However, the complete spectrum of KRAS targets that mediate its tumorigenic effect has not yet been fully delineated. We identified bone morphogenetic protein 4 (Bmp4), a transforming growth factor-β family member that regula...

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Главные авторы: Duerr, Eva-Maria, Mizukami, Yusuke, Moriichi, Kentaro, Gala, Manish, Jo, Won-Seok, Kikuchi, Hirotoshi, Xavier, Ramnik J., Chung, Daniel C.
Формат: Artigo
Язык:Inglês
Опубликовано: American Physiological Society 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3362092/
https://ncbi.nlm.nih.gov/pubmed/22383492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00047.2011
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