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Germline Mutations in Oncogene-Induced Senescence Pathways are Associated with Multiple Sessile Serrated Adenomas
BACKGROUND & AIMS: Little is known about the genetic factors that contribute to development of sessile serrated adenomas (SSAs). SSAs contain somatic mutations in BRAF or KRAS early in development. However, evidence from humans and mouse models indicates that these mutations result in oncogene-i...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3978775/ https://ncbi.nlm.nih.gov/pubmed/24512911 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2013.10.045 |
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