Germline Mutations in Oncogene-Induced Senescence Pathways are Associated with Multiple Sessile Serrated Adenomas

BACKGROUND & AIMS: Little is known about the genetic factors that contribute to development of sessile serrated adenomas (SSAs). SSAs contain somatic mutations in BRAF or KRAS early in development. However, evidence from humans and mouse models indicates that these mutations result in oncogene-i...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Gala, Manish K., Mizukami, Yusuke, Le, Long P., Moriichi, Kentaro, Austin, Thomas, Yamamoto, Masayoshi, Lauwers, Gregory Y., Bardeesy, Nabeel, Chung, Daniel C.
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3978775/
https://ncbi.nlm.nih.gov/pubmed/24512911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2013.10.045
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires