Oncogenic KRAS regulates BMP4 expression in colon cancer cell lines

Activating mutations in the KRAS oncogene are common in colorectal cancer. However, the complete spectrum of KRAS targets that mediate its tumorigenic effect has not yet been fully delineated. We identified bone morphogenetic protein 4 (Bmp4), a transforming growth factor-β family member that regula...

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Bibliographische Detailangaben
Hauptverfasser: Duerr, Eva-Maria, Mizukami, Yusuke, Moriichi, Kentaro, Gala, Manish, Jo, Won-Seok, Kikuchi, Hirotoshi, Xavier, Ramnik J., Chung, Daniel C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2012
Schlagworte:
Cancer Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3362092/
https://ncbi.nlm.nih.gov/pubmed/22383492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00047.2011
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