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Interleukin-1β-induced barrier dysfunction is signaled through PKC-θ in human brain microvascular endothelium
Blood-brain barrier dysfunction is a serious consequence of inflammatory brain diseases, cerebral infections, and trauma. The proinflammatory cytokine interleukin (IL)-1β is central to neuroinflammation and contributes to brain microvascular leakage and edema formation. Although it is well known tha...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3362001/ https://ncbi.nlm.nih.gov/pubmed/22403784 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00371.2011 |
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