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Suppression of intestinal calcium entry channel TRPV6 by OCRL, a lipid phosphatase associated with Lowe syndrome and Dent disease

Oculocerebrorenal syndrome of Lowe (OCRL) gene product is a phosphatidyl inositol 4,5-bisphosphate [PI(4,5)P(2)] 5-phosphatase, and mutations of OCRL cause Lowe syndrome and Dent disease, both of which are frequently associated with hypercalciuria. Transient receptor potential, vanilloid subfamily,...

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Detalhes bibliográficos
Main Authors: Wu, Guojin, Zhang, Wei, Na, Tao, Jing, Haiyan, Wu, Hongju, Peng, Ji-Bin
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3361998/
https://ncbi.nlm.nih.gov/pubmed/22378746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00277.2011
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