Dysregulation Of Innate Immunity In HCV Genotype 1 IL28B Unfavorable Genotype Patients: Impaired Viral Kinetics And Therapeutic Response

Recent studies have shown that a single nucleotide polymorphism upstream of the interleukin (IL)-28B gene plays a major role in predicting therapeutic response in HCV-infected patients treated with pegylated interferon-alpha (IFN)/ribavirin. We sought to investigate the mechanism of the IL28B polymo...

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Autores principales: Naggie, Susanna, Osinusi, Anu, Katsounas, Antonios, Lempicki, Richard, Herrmann, Eva, Thompson, Alexander J, Clark, Paul J, Patel, Keyur, Muir, Andrew J, McHutchison, John G, Schlaak, Joerg F, Trippler, Martin, Shivakumar, Bhavana, Masur, Henry, Polis, Michael A., Kottilil, Shyam
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3361636/
https://ncbi.nlm.nih.gov/pubmed/22331604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.25647
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