ITPA Gene Polymorphisms Significantly Affect Hemoglobin Decline and Treatment Outcomes in Patients Coinfected With HIV and HCV

Published studies have described a strong association with a single-nucleotide polymorphism (SNP) in the inosine triphosphate pyrophosphatase (ITPA) gene and ribavirin (RBV)-induced hemolytic anemia in HCV-infected patients receiving pegylated interferon (pegIFN) and RBV. This study sought to evalua...

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Main Authors: Osinusi, Anu, Naggie, Susanna, Poonia, Seerat, Trippler, Martin, Hu, Zonghui, Funk, Emily, Schlaak, Joerg, Fishbein, Dawn, Masur, Henry, Polis, Michael, Kottilil, Shyam
Format: Artigo
Language:Inglês
Published: 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518921/
https://ncbi.nlm.nih.gov/pubmed/22585729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jmv.23302
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