Adaptor protein-3 is required in dendritic cells for optimal Toll-like receptor signaling from phagosomes and antigen presentation to CD4(+) T cells

Effective major histocompatibility complex-II (MHC-II) antigen presentation from phagocytosed particles requires phagosome-intrinsic toll-like receptor (TLR) signaling, but the molecular mechanisms underlying TLR delivery to phagosomes and how signaling regulates antigen presentation are incompletel...

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Detalhes bibliográficos
Main Authors: Mantegazza, Adriana R., Guttentag, Susan H., El-Benna, Jamel, Sasai, Miwa, Iwasaki, Akiko, Shen, Hao, Laufer, Terri M., Marks, Michael S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3361531/
https://ncbi.nlm.nih.gov/pubmed/22560444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2012.02.018
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