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Inversion of neurovascular coupling by subarachnoid blood depends on large-conductance Ca(2+)-activated K(+) (BK) channels

The cellular events that cause ischemic neurological damage following aneurysmal subarachnoid hemorrhage (SAH) have remained elusive. We report that subarachnoid blood profoundly impacts communication within the neurovascular unit—neurons, astrocytes, and arterioles—causing inversion of neurovascula...

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Detalhes bibliográficos
Main Authors: Koide, Masayo, Bonev, Adrian D., Nelson, Mark T., Wellman, George C.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3361424/
https://ncbi.nlm.nih.gov/pubmed/22547803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1121359109
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