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Reduced Ca(2+) spark activity after subarachnoid hemorrhage disables BK channel control of cerebral artery tone

Intracellular Ca(2+) release events (‘Ca(2+) sparks') and transient activation of large-conductance Ca(2+)-activated potassium (BK) channels represent an important vasodilator pathway in the cerebral vasculature. Considering the frequent occurrence of cerebral artery constriction after subarach...

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Detalhes bibliográficos
Main Authors: Koide, Masayo, Nystoriak, Matthew A, Krishnamoorthy, Gayathri, O'Connor, Kevin P, Bonev, Adrian D, Nelson, Mark T, Wellman, George C
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049462/
https://ncbi.nlm.nih.gov/pubmed/20736958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2010.143
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