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The chromatin remodeling complex NuRD establishes the poised state of rRNA genes characterized by bivalent histone modifications and altered nucleosome positions

rRNA genes (rDNA) exist in two distinct epigenetic states, active promoters being unmethylated and marked by euchromatic histone modifications, whereas silent ones are methylated and exhibit heterochromatic features. Here we show that the nucleosome remodeling and deacetylation (NuRD) complex establ...

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Bibliografiske detaljer
Main Authors: Xie, Wenbing, Ling, Te, Zhou, Yonggang, Feng, Weijun, Zhu, Qiaoyun, Stunnenberg, Henk G., Grummt, Ingrid, Tao, Wei
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3361413/
https://ncbi.nlm.nih.gov/pubmed/22570494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1201262109
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