The chromatin remodeling complex NuRD establishes the poised state of rRNA genes characterized by bivalent histone modifications and altered nucleosome positions

rRNA genes (rDNA) exist in two distinct epigenetic states, active promoters being unmethylated and marked by euchromatic histone modifications, whereas silent ones are methylated and exhibit heterochromatic features. Here we show that the nucleosome remodeling and deacetylation (NuRD) complex establ...

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Detalles Bibliográficos
Main Authors: Xie, Wenbing, Ling, Te, Zhou, Yonggang, Feng, Weijun, Zhu, Qiaoyun, Stunnenberg, Henk G., Grummt, Ingrid, Tao, Wei
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2012
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3361413/
https://ncbi.nlm.nih.gov/pubmed/22570494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1201262109
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