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Genetic coregulation of age of female sexual maturation and lifespan through circulating IGF1 among inbred mouse strains
We previously reported that mouse strains with lower circulating insulin-like growth factor 1 (IGF1) level at 6 mo have significantly extended longevity. Here we report that strains with lower IGF1 have significantly delayed age of female sexual maturation, measured by vaginal patency (VP). Among st...
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| Główni autorzy: | , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
National Academy of Sciences
2012
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3361401/ https://ncbi.nlm.nih.gov/pubmed/22566614 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1121113109 |
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