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Genetic Regulation of Female Sexual Maturation and Longevity Through Circulating IGF1

We previously reported that insulin-like growth factor 1 (IGF1) was involved in coregulating female sexual maturation and longevity. To understand the underlying genetic mechanisms, based on the strain survey assays of development and aging traits, we crossed two mouse strains, KK/HIJ and PL/J, and...

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Detalhes bibliográficos
Publicado no:J Gerontol A Biol Sci Med Sci
Main Authors: Yuan, Rong, Gatti, Daniel M., Krier, Rebecca, Malay, Ethan, Schultz, David, Peters, Luanne L., Churchill, Gary A., Harrison, David E., Paigen, Beverly
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4481683/
https://ncbi.nlm.nih.gov/pubmed/25070661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glu114
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