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Reversal of muscle insulin resistance by weight reduction in young, lean, insulin-resistant offspring of parents with type 2 diabetes

To examine the role of intramyocellular lipid (IMCL) accumulation as well as circulating cytokines, branched-chain amino acids and acylcarnitines in the pathogenesis of muscle insulin resistance in healthy, young, lean insulin-resistant offspring of parents with type 2 diabetes (IR offspring), we me...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Petersen, Kitt Falk, Dufour, Sylvie, Morino, Katsutaro, Yoo, Peter S., Cline, Gary W., Shulman, Gerald I.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3361376/
https://ncbi.nlm.nih.gov/pubmed/22547801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1205675109
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