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Cooperation between Shh and IGF-I in Promoting Myogenic Proliferation and Differentiation via the MAPK/ERK and PI3K/Akt Pathways Requires Smo Activity
Sonic hedgehog (Shh) has been shown to promote adult myoblast proliferation and differentiation and affect Akt phosphorylation via its effector Smoothened (Smo). Here, the relationship between Shh and IGF-I was examined with regard to myogenic differentiation via signaling pathways which regulate th...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3360966/ https://ncbi.nlm.nih.gov/pubmed/21618536 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.22861 |
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