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Independent and cooperative roles of the Mek/ERK1/2-MAPK and PI3K/Akt/mTOR pathways during developmental myelination and in adulthood

Multiple extracellular and intracellular signals regulate the functions of oligodendrocytes as they progress through the complex process of developmental myelination and then maintain a functionally intact myelin sheath throughout adult life, preserving the integrity of the axons. Recent studies sug...

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Publicado en:Glia
Main Authors: Ishii, Akihiro, Furusho, Miki, Macklin, Wendy, Bansal, Rashmi
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6571146/
https://ncbi.nlm.nih.gov/pubmed/30761608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.23602
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