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Signaling by FGF Receptor 2, Not FGF Receptor 1, Regulates Myelin Thickness through Activation of ERK1/2–MAPK, Which Promotes mTORC1 Activity in an Akt-Independent Manner
FGF signaling has emerged as a significant “late-stage” regulator of myelin thickness in the CNS, independent of oligodendrocyte differentiation. Therefore, it is critically important to identify the specific FGF receptor type and its downstream signaling molecules in oligodendrocytes to obtain bett...
Sparad:
| I publikationen: | J Neurosci |
|---|---|
| Huvudupphovsmän: | , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Society for Neuroscience
2017
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5354334/ https://ncbi.nlm.nih.gov/pubmed/28193689 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3316-16.2017 |
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