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A conserved role of IQGAP1 in regulating TOR complex 1

Defining the mechanisms that control cell growth and division is crucial to understanding cell homeostasis, which impacts human diseases such as cancer and diabetes. IQGAP1, a widely conserved effector and/or regulator of the GTPase CDC42, is a putative oncoprotein that controls cell proliferation;...

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Hlavní autoři: Tekletsadik, Yemsrach K., Sonn, Robert, Osman, Mahasin A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Company of Biologists 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3360921/
https://ncbi.nlm.nih.gov/pubmed/22328503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.098947
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