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IQGAP1 regulates cell proliferation through a novel CDC42-mTOR pathway

Cell proliferation requires close coordination of cell growth and division to ensure constant cell size through the division cycles. IQGAP1, an effector of CDC42 GTPase has been implicated in the modulation of cell architecture, regulation of exocytosis and in human cancers. The precise mechanism un...

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Hlavní autoři: Wang, Jian-Bin, Sonn, Robert, Tekletsadik, Yemmsrach K., Samorodnitsky, Daniel, Osman, Mahasin A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Company of Biologists 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2723156/
https://ncbi.nlm.nih.gov/pubmed/19454477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.044644
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