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An Emerging Role for IQGAP1 in Regulating Protein Traffic

IQGAP1, an effector of CDC42p GTPase, is a widely conserved, multifunctional protein that bundles F-actin through its N-terminus and binds microtubules through its C-terminus to modulate the cell architecture. It has emerged as a potential oncogene associated with diverse human cancers. Therefore, I...

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Autore principale: Osman, Mahasin
Natura: Artigo
Lingua:Inglês
Pubblicazione: TheScientificWorldJOURNAL 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3217317/
https://ncbi.nlm.nih.gov/pubmed/20495773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1100/tsw.2010.85
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