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Functional Analysis of a Breast Cancer-Associated Mutation in the Intracellular Domain of the Metalloprotease ADAM12

A recently identified breast cancer-associated mutation in the metalloprotease ADAM12 alters a potential dileucine trafficking signal, which could affect protein processing and cellular localization. ADAM12 belongs to the group of A Disintegrin And Metalloproteases (ADAMs), which are typically membr...

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書目詳細資料
Main Authors: Stautz, Dorte, Wewer, Ulla M., Kveiborg, Marie
格式: Artigo
語言:Inglês
出版: Public Library of Science 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3360752/
https://ncbi.nlm.nih.gov/pubmed/22662180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037628
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