Using Prior Information from the Medical Literature in GWAS of Oral Cancer Identifies Novel Susceptibility Variant on Chromosome 4 - the AdAPT Method

BACKGROUND: Genome-wide association studies (GWAS) require large sample sizes to obtain adequate statistical power, but it may be possible to increase the power by incorporating complementary data. In this study we investigated the feasibility of automatically retrieving information from the medical...

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Autori principali: Johansson, Mattias, Roberts, Angus, Chen, Dan, Li, Yaoyong, Delahaye-Sourdeix, Manon, Aswani, Niraj, Greenwood, Mark A., Benhamou, Simone, Lagiou, Pagona, Holcátová, Ivana, Richiardi, Lorenzo, Kjaerheim, Kristina, Agudo, Antonio, Castellsagué, Xavier, Macfarlane, Tatiana V., Barzan, Luigi, Canova, Cristina, Thakker, Nalin S., Conway, David I., Znaor, Ariana, Healy, Claire M., Ahrens, Wolfgang, Zaridze, David, Szeszenia-Dabrowska, Neonilia, Lissowska, Jolanta, Fabiánová, Eleonóra, Mates, Ioan Nicolae, Bencko, Vladimir, Foretova, Lenka, Janout, Vladimir, Curado, Maria Paula, Koifman, Sergio, Menezes, Ana, Wünsch-Filho, Victor, Eluf-Neto, Jose, Boffetta, Paolo, Franceschi, Silvia, Herrero, Rolando, Fernandez Garrote, Leticia, Talamini, Renato, Boccia, Stefania, Galan, Pilar, Vatten, Lars, Thomson, Peter, Zelenika, Diana, Lathrop, Mark, Byrnes, Graham, Cunningham, Hamish, Brennan, Paul, Wakefield, Jon, Mckay, James D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3360735/
https://ncbi.nlm.nih.gov/pubmed/22662130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036888
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