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Identification and Function of Exchange Proteins Activated Directly by Cyclic AMP (Epac) in Mammalian Spermatozoa

The role of cAMP in spermatic functions was classically thought to be mediated exclusively through the activation of Protein Kinase A (PKA). However, it has recently been shown that cAMP also exerts its effects through a PKA-independent pathway activating a family of proteins known as Epac proteins....

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Detalhes bibliográficos
Main Authors: Miro-Moran, Alvaro, Jardin, Isaac, Ortega-Ferrusola, Cristina, Salido, Gines M., Peña, Fernando J., Tapia, Jose A., Aparicio, Ines M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3360633/
https://ncbi.nlm.nih.gov/pubmed/22662198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037713
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