Conditional Ablation of Gata4 and Fog2 Genes in Mice Reveals their Distinct Roles in Mammalian Sexual Differentiation

Assembly of functioning testis and ovary requires a GATA4-FOG2 transcriptional complex. To define the separate roles for GATA4 and FOG2 proteins in sexual development of the testis we have ablated the corresponding genes in somatic gonadal cells. We have established that GATA4 is required for testis...

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Hlavní autoři: Manuylov, N.L., Zhou, B., Ma, Q., Fox, S.C., Pu, W.T., Tevosian, S.G.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3360587/
https://ncbi.nlm.nih.gov/pubmed/21385577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2011.02.032
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