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Conditional Ablation of Gata4 and Fog2 Genes in Mice Reveals their Distinct Roles in Mammalian Sexual Differentiation
Assembly of functioning testis and ovary requires a GATA4-FOG2 transcriptional complex. To define the separate roles for GATA4 and FOG2 proteins in sexual development of the testis we have ablated the corresponding genes in somatic gonadal cells. We have established that GATA4 is required for testis...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3360587/ https://ncbi.nlm.nih.gov/pubmed/21385577 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2011.02.032 |
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