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The Regulation of Sox9 Gene Expression by the GATA4/FOG2 Transcriptional Complex in Dominant XX Sex Reversal Mouse Models.

We have previously established an in vivo requirement for GATA4 and FOG2 transcription factors in sexual differentiation. Fog2 null mouse fetuses or fetuses homozygous for a targeted mutation in Gata4 (Gata4(ki)), which cripples the GATA4-FOG2 interaction, exhibit a profound and early block in testi...

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Detalhes bibliográficos
Main Authors: Manuylov, Nikolay L., Fujiwara, Yuko, Adameyko, Igor I., Poulat, Francis, Tevosian, Sergei G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2020840/
https://ncbi.nlm.nih.gov/pubmed/17540364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2007.04.040
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