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ADAM17 regulates TNFα production by placental trophoblasts

Increased trophoblast TNFα production is an important component of placental dysfunction in preeclampsia. However, the mechanism of increased TNFα production in the preeclamptic placenta is largely unknown. ADAM17 is a metallopeptidase that functions as a TNFα converting enzyme. In this study, we ex...

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Bibliografiset tiedot
Päätekijät: Rong, Ma, Yang, Gu, Groome, Lynn J., Wang, Yuping
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3360543/
https://ncbi.nlm.nih.gov/pubmed/22018416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.placenta.2011.09.015
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