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ADAM17 regulates TNFα production by placental trophoblasts

Increased trophoblast TNFα production is an important component of placental dysfunction in preeclampsia. However, the mechanism of increased TNFα production in the preeclamptic placenta is largely unknown. ADAM17 is a metallopeptidase that functions as a TNFα converting enzyme. In this study, we ex...

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Detalhes bibliográficos
Main Authors: Rong, Ma, Yang, Gu, Groome, Lynn J., Wang, Yuping
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3360543/
https://ncbi.nlm.nih.gov/pubmed/22018416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.placenta.2011.09.015
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