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1,25(OH)(2)D(3) suppresses COX-2 up-regulation and thromboxane production in placental trophoblast cells in response to hypoxic stimulation
In this study, we determined if vitamin D could inhibit oxidative stress-induced thromboxane production by placental trophoblasts. Trophoblast isolated from normal placentas were stimulated with CoCl(2), a hypoxic mimicking agent, with or without pretreatment of 1,25(OH)(2)D(3). Soluble phospholipas...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4017579/ https://ncbi.nlm.nih.gov/pubmed/24374095 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.placenta.2013.12.002 |
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