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RON RECEPTOR TYROSINE KINASE NEGATIVELY REGULATES TNFα PRODUCTION IN ALVEOLAR MACROPHAGES BY INHIBITING NF-κB ACTIVITY AND ADAM17 PRODUCTION

The Ron receptor tyrosine kinase plays a regulatory role in the inflammatory response to acute lung injury induced by intranasal administration of bacterial lipopolysaccharide (LPS). Previously, we have showen that mice with a targeted deletion of the tyrosine kinase (TK) signaling domain of the Ron...

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Detalhes bibliográficos
Main Authors: Nikolaidis, Nikolaos M., Gray, Jerilyn K, Gurusamy, Devikala, Fox, William, Stuart, William D, Huber, Nathan, Waltz, Susan E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4082961/
https://ncbi.nlm.nih.gov/pubmed/19487969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0b013e3181ae8155
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