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G protein-coupled adenosine (P1) and P2Y receptors: ligand design and receptor interactions

The medicinal chemistry and pharmacology of the four subtypes of adenosine receptors (ARs) and the eight subtypes of P2Y receptors (P2YRs, activated by a range of purine and pyrimidine mono- and dinucleotides) has recently advanced significantly leading to selective ligands. X-ray crystallographic s...

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Détails bibliographiques
Auteurs principaux: Jacobson, Kenneth A., Balasubramanian, Ramachandran, Deflorian, Francesca, Gao, Zhan-Guo
Format: Artigo
Langue:Inglês
Publié: Springer Netherlands 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3360101/
https://ncbi.nlm.nih.gov/pubmed/22371149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-012-9294-7
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