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Multiple RNA binding domains of Bruno confer recognition of diverse binding sites for translational repression

Bruno protein binds to multiple sites—BREs—in the oskar mRNA 3′ UTR, thereby controlling oskar mRNA translation. Bruno also binds and regulates other mRNAs, although the binding sites have not yet been defined. Bruno has three RRM type RNA binding motifs, two near the amino terminus and an extended...

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Bibliografiske detaljer
Main Authors: Reveal, Brad, Garcia, Carlos, Ellington, Andy, Macdonald, Paul M
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3360078/
https://ncbi.nlm.nih.gov/pubmed/21955496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.8.6.17542
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