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Region-Specific Activation of oskar mRNA Translation by Inhibition of Bruno-Mediated Repression

A complex program of translational repression, mRNA localization, and translational activation ensures that Oskar (Osk) protein accumulates only at the posterior pole of the Drosophila oocyte. Inappropriate expression of Osk disrupts embryonic axial patterning, and is lethal. A key factor in transla...

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Bibliografiske detaljer
Udgivet i:PLoS Genet
Main Authors: Kim, Goheun, Pai, Chin-I, Sato, Keiji, Person, Maria D., Nakamura, Akira, Macdonald, Paul M.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4344327/
https://ncbi.nlm.nih.gov/pubmed/25723530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004992
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