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Reconsideration of In-Silico siRNA Design Based on Feature Selection: A Cross-Platform Data Integration Perspective

RNA interference via exogenous short interference RNAs (siRNA) is increasingly more widely employed as a tool in gene function studies, drug target discovery and disease treatment. Currently there is a strong need for rational siRNA design to achieve more reliable and specific gene silencing; and to...

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Detalhes bibliográficos
Main Authors: Liu, Qi, Zhou, Han, Cui, Juan, Cao, Zhiwei, Xu, Ying
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3360065/
https://ncbi.nlm.nih.gov/pubmed/22655076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037879
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