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Integrated siRNA design based on surveying of features associated with high RNAi effectiveness

BACKGROUND: Short interfering RNAs have allowed the development of clean and easily regulated methods for disruption of gene expression. However, while these methods continue to grow in popularity, designing effective siRNA experiments can be challenging. The various existing siRNA design guidelines...

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Detalhes bibliográficos
Main Authors: Gong, Wuming, Ren, Yongliang, Xu, Qiqi, Wang, Yejun, Lin, Dong, Zhou, Haiyan, Li, Tongbin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1698580/
https://ncbi.nlm.nih.gov/pubmed/17129386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-7-516
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