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In Silico Target-Specific siRNA Design Based on Domain Transfer in Heterogeneous Data

RNA interference via exogenous small interference RNAs (siRNA) is a powerful tool in gene function study and disease treatment. Designing efficient and specific siRNA on target gene remains the key issue in RNAi. Although various in silico models have been proposed for rational siRNA design, most of...

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Detalles Bibliográficos
Main Authors: Liu, Qi, Zhou, Han, Zhang, Kui, Shi, Xiaoxiao, Fan, Wei, Zhu, Ruixin, Yu, Philip S., Cao, Zhiwei
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3528743/
https://ncbi.nlm.nih.gov/pubmed/23284642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0050697
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