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In Silico Target-Specific siRNA Design Based on Domain Transfer in Heterogeneous Data

RNA interference via exogenous small interference RNAs (siRNA) is a powerful tool in gene function study and disease treatment. Designing efficient and specific siRNA on target gene remains the key issue in RNAi. Although various in silico models have been proposed for rational siRNA design, most of...

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Bibliografiska uppgifter
Huvudupphovsmän: Liu, Qi, Zhou, Han, Zhang, Kui, Shi, Xiaoxiao, Fan, Wei, Zhu, Ruixin, Yu, Philip S., Cao, Zhiwei
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2012
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3528743/
https://ncbi.nlm.nih.gov/pubmed/23284642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0050697
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