TLR2, TLR4 and the MYD88 Signaling Pathway Are Crucial for Neutrophil Migration in Acute Kidney Injury Induced by Sepsis

The aim of this study was to investigate the role of TLR2, TLR4 and MyD88 in sepsis-induced AKI. C57BL/6 TLR2(−/−), TLR4(−/−) and MyD88(−/−) male mice were subjected to sepsis by cecal ligation and puncture (CLP). Twenty four hours later, kidney tissue and blood samples were collected for analysis....

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Castoldi, Angela, Braga, Tárcio Teodoro, Correa-Costa, Matheus, Aguiar, Cristhiane Fávero, Bassi, Ênio José, Correa-Silva, Reinaldo, Elias, Rosa Maria, Salvador, Fábia, Moraes-Vieira, Pedro Manoel, Cenedeze, Marcos Antônio, Reis, Marlene Antônia, Hiyane, Meire Ioshie, Pacheco-Silva, Álvaro, Gonçalves, Giselle Martins, Câmara, Niels Olsen Saraiva
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3360043/
https://ncbi.nlm.nih.gov/pubmed/22655058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037584
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi