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Essential role for telomerase in chronic myeloid leukemia induced by BCR-ABL in mice

The telomerase protein is constitutively activated in malignant cells from many patients with cancer, including the chronic myeloid leukemia (CML), but whether telomerase is essential for the pathogenesis of this disease is not known. Here, we used telomerase deficient mice to determine the requirem...

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Detalhes bibliográficos
Main Authors: Vicente-Dueñas, Carolina, Barajas-Diego, Marcos, Romero-Camarero, Isabel, González-Herrero, Inés, Flores, Teresa, Sánchez-García, Isidro
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3359883/
https://ncbi.nlm.nih.gov/pubmed/22408137
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